No, it's not that Shark Attack one.
Upon reviewing this clip, I would argue it's not the most random line ever or worst line in scriptwriting history, but it may very well be the most terribly delivered line in non-uwe-boll video-game-adaptation movie history.
It could be randomer. I mean she says "you're still alive" and then she says "too bad you're going to die" so while it's not exactly the most sensible comeback it's not like it's completely without any context.
bad actors more than a bad line
almost feels like watching a hollywood movie from the 40-50s
Okay, I guess I was wrong about it being the most random line ever, but do to the way the line was delivered, I actually thought she just said "Too bad, you!" in the movie. That would be completely random, not to mention meaningless. Anyways, I encourage you to submit the line you think is the most random ever. I'm looking forward to what you have.